Billing & coverage
Clear costs up front. We verify coverage before any test runs, and if a patient would owe anything, they hear from us and approve it first.
Coverage first, testing second
- Step 1
Verify
We work with billers and the patient's plan to check eligibility and benefits.
- Step 2
Confirm any cost
If there's an out-of-pocket cost, we call the patient first.
- Step 3
Patient approves
Nothing moves forward without the patient's OK.
- Step 4
Test runs
The lab processes the sample and bills the insurer directly.
- Step 5
Statement
The patient may get an Explanation of Benefits from their plan.
We work with billers and insurers, so your team doesn't have to
Our program team works with billers and each patient's insurance plan to verify eligibility before a sample is tested.
Eligibility verification
Coverage and eligibility for PGx testing are checked with the patient's plan before the test runs.
Prior authorizations
When a plan requires prior authorization, our team submits and follows up on it.
Patient cost check
If a patient would have an out-of-pocket cost, we contact them and confirm they want to go ahead.
Physician coordination
We send the ordering physician the requisition and consent, and collect the signed requisition.
Claims to the insurer
The lab bills the patient's plan directly. Your organization doesn't submit the claim.
- A copy of the patient's insurance card
- Face sheet or demographic information
- Current medication list
- Signed informed consent
- Requisition signed by the ordering physician, with ICD-10 codes
- Pharmacies: the completed pharmacist recommendation form
Send documents by secure fax or email. Your program specialist will share the details when you enroll.
Who covers PGx testing
| Payer | Coverage | What's typically required |
|---|---|---|
| Medicare | When criteria are met | MolDX policy (LCD L38294): a clinician is considering or using a specific drug with an actionable gene-drug interaction (CPIC level A/B or FDA labeling) and needs the result for dosing or selection. Not covered on diagnosis alone. A multi-gene panel is covered only when more than one gene on it is needed. |
| Medicaid & Medi-Cal | Varies by state | Coverage rules vary by state. We verify each patient before testing. |
| Commercial plans | Varies by plan | Many plans cover PGx when their criteria are met. When a plan requires prior authorization, our team handles it. |
Your questions about cost
Will I get a bill?
Before testing, we tell you if you are expected to owe anything, and nothing proceeds without your approval.
I got a statement from my plan
An Explanation of Benefits (EOB) shows what your plan paid. It is not a bill. Keep it for your records.
Questions about a bill?
Call our billing team at (618) 224-4383 or email info@achievedx.com. Have your statement handy.
Document medical necessity
Clear documentation keeps claims moving. For Medicare (MolDX), record these in the chart and on the requisition. Testing isn't covered based on a diagnosis alone.
- The specific drug being considered or currently used
- That it has an actionable gene-drug interaction (CPIC level A/B or FDA labeling)
- How the result will guide dosing or drug selection
- That non-genetic factors were also considered
Common PGx CPT codes
For reference. The codes billed depend on the genes tested.
| CPT | Gene or panel |
|---|---|
| 81225 | CYP2C19 |
| 81226 | CYP2D6 |
| 81227 | CYP2C9 |
| 81355 | VKORC1 |
| 81328 | SLCO1B1 |
| 81335 | TPMT |
| 81418 | Drug metabolism panel |
Check coverage for your patients.
Three quick steps. A program specialist follows up with a recommended workflow, materials and a go-live timeline.
Your organization and the tests you pick will show here.
What kind of organization are you?
Which testing do you want to explore?
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Where should we send your program plan?
We use your information only to respond to your inquiry. Please don't include patient health information.
Thank you. Your request is in.
An AchieveDx program specialist will reach out to schedule a short discovery call and walk through your plan.
A specialist reads your answers before reaching out.
We learn your workflow, patient population and goals.
Recommended workflow, kits and materials, and a go-live timeline.
Frequently asked
Will patients get a surprise bill?
We work to prevent that. We verify coverage before testing, and if a patient would owe anything, we contact them first and they decide whether to go ahead.
Does Medicare cover PGx testing?
Yes, when its criteria are met: a clinician is considering or using a specific drug with an actionable gene-drug interaction (CPIC level A/B or FDA labeling) and needs the result for that decision. It is not covered based on a diagnosis alone.
Do you handle prior authorizations?
Yes. When a plan requires prior authorization, our team submits and follows up on it.
Who verifies coverage?
Our program team works with billers and each patient's insurance plan to verify eligibility and identify any patient cost before the test runs.
What does a patient do with an Explanation of Benefits?
Keep it for their records. An EOB shows what the plan paid and is not a bill.
PGx testing in 60 seconds
The same prescription can work differently for different people.
Almost half of spontaneously reported ADRs may have identifiable causes, most likely genetic.
And 3–6% of U.S. hospital admissions are related to adverse drug reactions.
Pharmacogenomic (PGx) testing reads the genes that control how your body processes medications.
It starts with one quick cheek swab.
No needles. No blood draw. Done in the pharmacy, the office or at the bedside.
Our CLIA-certified lab analyzes your DNA.
Coverage is verified first. Results 5–7 days after the lab receives the sample.
A pharmacist-reviewed report shows which medications fit your genes.
Test once. Use the results for life.
Your inherited genes don't change, so one result can inform many future prescriptions.
Coverage is checked before any test runs.
Coverage varies by plan. Any patient cost is confirmed first.
One quick test. Lifelong medication guidance.
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