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AchieveDxPharmacogenomicsCelemicsOncology NGS

Genomic testing for medication safety and cancer care.

From how a patient will respond to a medication to hereditary cancer risk and tumor profiling. Every result comes back as an interpreted, physician-ready report.

CLIA-certifiedHigh-complexity laboratory
Oncology panels by CelemicsHybrid-capture design for our NGS tests
Interpreted reportsClinVar and CIViC annotated
HIPAA safeguardsSecure handling of genetic data
Our testing

Two service lines. One laboratory partner.

Turnkey pharmacogenomic testing programs, and oncology NGS panels in partnership with Celemics. Offer one, or both, with the same lab, logistics and reporting.

AchieveDxPharmacogenomics
Medication response

PGx testing programs

A one-time cheek swab shows how a patient's genes may affect their response to medications, with a pharmacist-reviewed summary for the prescriber.

77medications
1cheek swab
5–7days after receipt
HospitalsPharmaciesSkilled nursingPhysician groups
AchieveDx×Celemics
Oncology

NGS cancer panels

Hybrid-capture panels for hereditary cancer risk, solid-tumor profiling and plasma ctDNA, each returned as an interpreted, physician-ready report.

5panels
15–54genes per panel
3specimen types
OncoRiskCancerScreen 50ctDNA ColorectalctDNA BreastctDNA Lung
What is PGx testing?

Your genes shape how every medication works for you

A pharmacogenomic test reads the genes that control how your body activates and clears medications. Prescribers use the results to choose drugs and doses that are more likely to work and less likely to cause side effects.

  • Test once, use it again. Your inherited genes don't change, so one result can inform many future prescriptions.
  • Clear, actionable reports. Each finding comes with a recommendation the prescriber can act on.
  • Backed by guidelines. CPIC guidance and pharmacogenomic information in the labeling of hundreds of FDA-approved drugs.14,15
Read: What is PGx testing?
How PGx testing works

From swab to prescribing decision

  1. Step 1

    Enroll

    A short enrollment form. We send kits, requisitions and patient materials.

    Kits shipped to you
  2. Step 2

    Collect

    A painless cheek swab in the pharmacy, office or at the bedside.

    No needles
  3. Step 3

    Analyze

    Coverage is verified first, then our CLIA-certified lab genotypes the sample.

    5–7 days after receipt
  4. Step 4

    Act

    A pharmacist-reviewed summary goes to the prescriber with clear recommendations.

    Pharmacist-reviewed
Pharmacogenomic testing programs

Where do you fit?

Turnkey PGx programs for hospitals, pharmacies, skilled nursing facilities and physician groups. Choose your setting to see how it runs.

Takes 10 seconds. Or call (618) 224-4383.

New to pharmacogenomics? Start with what PGx testing is

Why it matters

From trial and error to informed choices

Most prescriptions start with a best guess. A one-time PGx test adds the patient's genetics to that decision.

The usual approachTrial and error
First choice

Start with a common drug and see how the patient responds.

Dosing

Adjust over weeks based on side effects and response.

Side effects

Often found only after the patient experiences them.

Future prescriptions

Each new medication starts the guessing over.

With PGx testingInformed by genetics
First choice

Choose a drug with the patient's genetics already in mind.

Dosing

Start from a dose informed by how the patient processes the drug.

Side effects

Known gene-drug risks are flagged before prescribing.

Future prescriptions

One test result can inform the prescriptions that follow.

Coverage checked before any test runs

Medicare usually covers approved lab tests with no patient cost-share when its criteria are met. We verify each patient's coverage first. If a patient would owe anything, we contact them and get approval before testing.

Medicare, when criteria are metMedicaid & Medi-Cal, varies by stateCommercial, varies by plan
AchieveDx×Celemics

AchieveDx runs the lab and delivers every report.Celemics designs the oncology panels.

AchieveDx

A CLIA-certified, high-complexity laboratory. We run our own PGx testing, and handle kits, logistics, sequencing, analysis and interpreted reports for the oncology panels.

Celemics

Oncology panel design and hybrid-capture target enrichment, with more than 10 years designing NGS panels and ctDNA panels developed with Seoul National University Hospital.

Your team

Provides the right specimen and a completed requisition. No in-house bioinformatics needed.

Oncology NGS portfolio

Five panels across the cancer care pathway

Hereditary risk, somatic tumor profiling and plasma ctDNA analysis. Select a panel to see its specifications and full gene list.

HereditarySomaticLiquid biopsy
Hereditary · Whole blood

OncoRisk

Germline risk in a patient or family with a suspicious history.

31genes
Covered region
Whole CDS · 96 Kb
Variant types
SNV, indel, CNV
Sensitivity
97.9%
Specificity
>99%
Reporting
ACMG/AMP 2015, ClinVar and OMIM
  • Early-onset cancer or striking family history
  • Cascade testing of relatives
  • PARP inhibitor eligibility via BRCA1/2, PALB2 and HRR genes
  • Lynch syndrome workup
Genes on the panel
APCATMBARD1BLMBMPR1ABRCA1BRCA2BRIP1CDH1CDK4CDKN2ACHEK2EPCAMMLH1MRE11AMSH2MSH6MUTYHNBNPALB2PMS2PRSS1PTENRAD50RAD51CRAD51DSLX4SMAD4STK11TP53VHL

Manufacturer reference specifications from Celemics product sheets (OncoRisk OR-PS-v1.3, CancerScreen CSS-PS-v1.3, Liquid Biopsy LB-PS-v1.4). ctDNA performance measured with Seraseq reference material. All panels are sequenced on the Element AVITI platform.18

Full portfolio details
How NGS testing works

From specimen to interpreted report

Your team provides the specimen and requisition. We handle sequencing, analysis and clinical interpretation.

  1. Step 1

    Collect the right specimen

    Whole blood for OncoRisk, tumor tissue for CancerScreen 50, plasma for the ctDNA panels.

  2. Step 2

    Ship to AchieveDx

    Kits, requisitions and logistics are provided by our team.

  3. Step 3

    Hybrid-capture NGS

    Celemics target enrichment and sequencing on Element AVITI, with variant analysis and QC.

  4. Step 4

    Interpreted report

    Variant findings with evidence and clinical context, not a raw variant file.

Somatic Tumor Profiling ReportCancerScreen 50 · Sample · fictional patient
GeneEGFR
Alterationp.L858R
ClassSNV
EvidenceAMP/ASCO/CAP Tier I

From actionable variant to therapy

ContextFDA-approved therapy example
Metastatic NSCLCOsimertinib, first-line metastatic setting

Also in every report

ClinVarCIViCAMP/ASCO/CAP tierMatched clinical trialsQC metricsLimitations
Illustrative content, not a patient result. Does not imply companion-diagnostic approval.
1

Which variant is reported?

Gene, coding and protein change, and variant class, with ClinVar, CIViC and classification evidence.

2

What therapy evidence exists?

Actionable variants are matched to evidence levels, such as an AMP/ASCO/CAP Tier I therapy for EGFR L858R in metastatic NSCLC.

3

And if there isn't?

Relevant open clinical trials are listed by NCT ID, phase, biomarker and status, so the conversation can continue.

Every report closes with methodology, QC metrics, stated test limitations and a commitment to reclassify variants as new evidence is published. See sample reports

For health systems and laboratories

Bring these panels to your institution

Review sample reports, choose your starting panels and plan a pilot with our team.

  1. 1Select starting panels
  2. 2Review sample reports
  3. 3Confirm logistics
  4. 4Pilot with a defined cohort
Build your testing program

Tell us about your organization.

Three quick steps. A program specialist follows up with a recommended workflow, materials and a go-live timeline.

Your program so farNothing yet

Your organization and the tests you pick will show here.

Prefer to talk now?
(618) 224-4383
info@achievedx.com
Step 1 of 3Your organization

What kind of organization are you?

STEP 1We review your request

A specialist reads your answers before reaching out.

STEP 2A short discovery call

We learn your workflow, patient population and goals.

STEP 3Your program plan

Recommended workflow, kits and materials, and a go-live timeline.

Questions

Frequently asked

What is pharmacogenomic (PGx) testing?

A PGx test reads genes that control how your body activates and clears medications. Providers use the results to choose drugs and doses that are more likely to work and less likely to cause side effects.

How is the sample collected?

With a simple cheek swab. No needles or blood draw. It can be done in a pharmacy, physician office, hospital unit or at a resident's bedside.

How long do results take?

Typically 5–7 days after the lab receives the specimen. SNF programs receive results by encrypted email or fax within 5–10 business days.

How do we start offering the oncology panels?

Choose your starting panels, review sample reports with your oncology and pathology teams, confirm logistics, then run a pilot with a defined patient cohort. Contact us to begin.

What specimens does each panel need?

OncoRisk uses whole blood. CancerScreen 50 uses fresh-frozen or FFPE tumor tissue. The ctDNA panels use plasma from a whole blood draw.